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Job Calis

Principal Investigator

Emma Research

For the latest publications of this PI visit Job Calis – Amsterdam UMC
Calis, J.C.J. (Job) j.c.calis@amsterdamumc.nl


Research lineTechnical innovations to timely identify critically ill children
DepartmentPediatric Intensive Care Unit
Research Institute(s)AR&D
Amsterdam Public Health
DescriptionOver the past years this has been my major topic of research. Most recent success is that I secured a large EU grant (3.4 million euro) as the PI on the IMPALA project.
Seniors• Job van Woensel
Michael Boele van Hensbroek
Wieger Voskuijl
Mark Hoogendoorn (VU)
• Wendy Janssen (VU)
• Maria Villalobos (LUMC)
Projects
The IMPALA ProjectThis project, performed by 7 international institutes, is aimed at developing an innovative vital signs monitor to timley identify deterioration of critically ill children. The monitor applies several innovative techniques including new sensors, artificial intelligence and robust and simple hard and software sollutions. Currently 4 PhD student, 3 MSc and 1 MMED student participate in this project.
Big Data – Prediction modelling in paediatric critical careWilliam Nkhono (PhD-VU) contributes to the project Big Data – Prediction modelling in paediatric critical care. In collaboration with Mathematics VU dep of AI and Netherlands E-Health Learning Lab
Patient monitoring for low-resource settings, social science approachDaniel Mwale contributes to the project Patient monitoring for low-resource settings, social science approach. In collaboration with Amsterdam Institute for Global Health.
Integration of AI and other models in clinical healthcareMargot Rakers (PhD-LUMC) works on the project Integration of AI and other models in clinical healthcare.
usability of a patient monitoring in a low-resource settingLezzie Chirambo (MSc MUBAS) works on the project usability of a patient monitoring in a low-resource setting
(MSc MUBAS): Alarms, thresholds and predictive valueChristina Chiziwa (MSc MUBAS) works on the project Alarms, thresholds and predictive value
Performance of early warning scores in Malawian HDU patientsJames Makina (MMED KUHeS) works on the projects performance of early warning scores in Malawian HDU patients

Research lineCirculatory failure & Severe anaemia
DepartmentPediatric Intensive Care Unit
Research Institute(s)AR&D
Amsterdam Public Health
DescriptionOver the past 20 years several studies concerning severe anaemia (my PhD and consecutive PhD’s I supervised) and circulation were done.
Seniors• Job van Woensel
Michael Boele van Hensbroek
Projects
CISSAC StudyRoxanne Assies PhD UvA en Mercy Kumwenda MMED KUHeS) contribute to this combination of studies: a) new techniques (CRI and HRV) to identify children with shock b) new bedside Ultrasound protocol to type shock and c) a descriptive study about prevalence and characteristics of shock

Research lineSevere infectious diseases in paediatrics
DepartmentPediatric Intensive Care Unit
Research Institute(s)AR&D
Amsterdam Public Health
Amsterdam institute for Immunology and Infectious diseases
DescriptionImproving care of life threatening infections. I supervised 4 PhD students (Sigaloff, Boender, Boerma, Huibers) in the field of HIV care and studied severe bacterial and viral infections in African children, PICU in the Netherlands and the carribean.
Seniors• Job van Woensel
Michael Boele van Hensbroek
Reinout Bem
Projects
Validation of the new Phoenix Sepsis score in the PICU in MalawiCharissa Verkade works on validation of the new Phoenix Sepsis score in the PICU in Malawi
Validation of CRP as a biomarker for bacteraemia and malaria in a hospitalized children with and without severe anaemiaMarijke Dorhoutmees works on the validation of CRP as a biomarker for bacteraemia and malaria in a hospitalized children with and without severe anaemia
The IMPALA projectJacqueline Msefula and Margaret Havara investigate existing and novel biomarkers to distinguish bacterial, viral and malaria infection in Malawi

Research lineSevere infectious diseases in paediatrics
DepartmentPediatric Intensive Care Unit
Research Institute(s)AR&D
Amsterdam Public Health
DescriptionNewest area of research which focuses on setting up High and intensive care facilities and services in LMIC. We published our experience setting up the first PICU in Malawi, reviewed the literature on this topic and combine health systems with medical education and
Seniors• Job van Woensel
Wieger Voskuijl
• Jacqueline Broers
• Saba Hinrichs-Krapels (TU Delft)
Projects
Health systems and development of paediHenderson Chitimoni investigates health systems and development of paediatric critical care in LRS
A set of studies on development and evaluation of training in paediatric critical care in LMICJ Langton contributes to a set of studies on development and evaluation of training in paediatric critical care in LMIC

Research lineSevere infectious diseases in paediatrics
DepartmentPediatric Intensive Care Unit
Research Institute(s)AR&D
DescriptionIn this research line we aim to improve timely recognition of pediatric critical illness through innovative monitoring. In addition, we aim to discriminate with innovative techniques between different forms of shock
Seniors• Dr Job C. Calis, PI
• Prof Dr Job B.M. van Woensel, PI
Projects• The IMPALA Study (Naam ) investigates …

Last edited: 05-03-2026