For the latest publications of this PI visit Taco Kuijpers – Amsterdam UMC
Kuijpers, T.W. (Taco) t.w.kuijpers@amsterdamumc.nl
| Research line | Pediatric Immunology |
|---|---|
| Department | Pediatric Infectious Diseases, Rheumatology and Immunology |
| Research Institute(s) | Amsterdam institute for Immunology & Infectious diseases |
| Description | This research line aims to determine the impact of immune dysfunction in genetically determined so-called “inborn errors of immunity (IEIs)” and various conditions of induced (acquired) innate or adaptive immune dysregulation. To these conditions, (auto)inflammatory and B-cell immune-mediated disorders (B-IMDs) are being focused on. In the realm of infection and inflammatory diseases in children we try to find an RNA- and/or protein-based signature to distinguish large categories of disease as a “super-CRP” in a large European consortium to categories to guide diagnostics and treatment in a faster and more certain fashion. |
| Seniors | • Taco Kuijpers, PI • Helin Tercan (Sanquin) en Celine Mahieu (Sanquin), postdocs • Giske Biesbroek (AMC), clinical fellow ped rheumatology, coordinator DIAMONDS study |
| Projects | |
| NK CAR cells for cancer treatment: functionality and production. | NK CAR cells for cancer treatment: functionality and production. |
| T2B-iCARE | This study investigates when to apply novel immune therapies – including CART - in B-cell immune-mediated disorders |
| BTHS iPSC neutrophil development | BTHS iPSC neutrophil development |
| Neutrophil extracellular trap formation (NETs): mechanisms of action | Neutrophil extracellular trap formation (NETs): mechanisms of action |
| Role of neutrophil activation and cell death by NET formation in TRALI | Role of neutrophil activation and cell death by NET formation in TRALI |
| Autoimmune disease: imbalances with a signature (Immune Health Seed) | Autoimmune disease: imbalances with a signature (Immune Health Seed) |
| Inborn errors of immunity: molecular mechanisms, NFkB activation and interferonopathies. | Inborn errors of immunity: molecular mechanisms, NFkB activation and interferonopathies. |
| Kawasaki Disease | Kawasaki Disease |
| DIAMONDS |
Last edited: 05-03-2026