For the latest publications of this PI visit Willemijn Corpeleijn – Amsterdam UMC
Corpeleijn, W.E. (Willemijn) w.e.corpeleijn@amsterdamumc.nl
| Research line | Familiaire Hypercholesterolemie |
|---|---|
| Department | Pediatric metabolic diseases |
| Research Institute(s) | Amsterdam Gastroenterology Endocrinology Metabolism |
| Description | Our research focuses on the treatment and outcomes of children with Familial Hypercholesterolemia (FH). FH is a genetic disorder that leads to high cholesterol levels, increasing the risk of cardiovascular disease from a young age. Our research aims to understand how early intervention can improve long-term health outcomes for individuals with FH. We are investigating various treatment strategies, monitoring their effects on cholesterol levels, and evaluating potential impacts on the prevention of heart disease. By closely tracking both short-term and long-term results, we hope to enhance the understanding of atherosclerosis in FH and develop optimized treatment protocols. Ultimately, our goal is to improve the quality of life and lifespan for children diagnosed with this condition. Furthermore we investigate the role of high Lp(a) in childhood. |
| Seniors | • W.E. Corpeleijn, Kinderarts metabole ziekten • B. Hutten, klinisch epidemioloog, UHD • B. Wiegman, kinderarts |
| Projects | |
| The QoL Study | Study in children and adults with homozygous FH |
| Follow-up of a large cohort of adults who were diagnosed with FH as children | Sibbeliene van den Bosch contributes to a follow-up of a large cohort of adults who were diagnosed with FH as children (PhD: Sibbeliene vd Bosch) |
| Cascade screening for high Lp(a) | Sibbeliene van den Bosch investigates cascade screening for high Lp(a) |
| cIMT measurements in the doctor’s office | Sibbeliene van den Bosch and F. Kowsoleea investigate cIMT measurements in the doctor’s office |
| Incidence of statin intolerance in childhood | Sibbeliene van den Bosch and F. Kowsoleea investigate the incidence of statin intolerance in childhood |
Last edited: 05-03-2026